WHAT IS THE ONWARD STUDY?

ONWARD is clinical research studies for patients with metastatic cancer who are progesterone receptor positive (PR+). ONWARD is named after onapristone, the active pharmaceutical ingredient in our investigational medicine.

WHAT PATIENT POPULATIONS WILL BE EVALUATED?

ONWARD 201: will evaluate Apristor in second line (2L) metastatic breast cancer patients who are progesterone receptor positive (PR+) and who have failed prior antiestrogen monotherapy or the combination of an antiestrogen plus a Cdk4/6 inhibitor.

ONWARD 203: will evaluate Apristor in pre-surgical treatment naive breast cancer patients alone and in combination with standard of care agents.